In the past I promoted 130+ programs, but I discovered the famous 20/80 rule applied to me as well. Meaning 20 percent of the promoted programs generate 80 percent of my income. So I picked the 50 best performing programs and ditched the rest. I stick to 50 and only add&remove one or two programs every month. Not closed the old accounts though, since they still might generate some revenue in the future.
"Depend on the rabbit's foot if you like, but remember it didn't work for the rabbit." R.E. Shay